在药物输送中应用的聚合物基基:概述
Nguyen Hoc Thang1, Truong Bach Chien1, Dang Xuan Cuong2
1Faculty of Chemical Technology, Ho Chi Minh City University of Food Industry, 140 Le Trong Tan, Tan Phu Distrist, Ho Chi Minh City 700000, Vietnam.
Gels (Basel, Switzerland)
|July 28, 2023
概括
聚合物水凝正在推进药物输送,提供受控释放和个性化医疗应用. 未来的发展重点是增强性质,向性交付和组合疗法,以改善患者的治疗结果.
科学领域:
- 材料科学 材料科学 材料科学
- 生物医学工程 生物医学工程
- 药理学 药理学是指药理学的学科.
背景情况:
- 聚合物水凝是具有高含水量的交叉连接的水友网络,由于可调节性质和生物相容性,它们非常适合药物输送.
- 目前的研究重点是对刺激反应的水凝 (pH,温度,酶) 进行向药物释放和降低系统毒性.
- 可注射配方和纳米水凝正在出现,以提高可用性和提高药物加载/释放效率.
研究的目的:
- 审查聚合物基水凝药物递送系统的发展趋势.
- 突出水凝特性方面的进步,包括机械强度和受控释放动力学.
- 探索水凝在个性化医学和复杂的治疗策略中的潜力.
主要方法:
- 关于聚合物凝合成和药物输送应用的最新进展的文献综述.
- 分析新兴趋势,如刺激响应系统,注射配方和纳米水凝等.
- 探索水凝在个性化医疗,多药物输送和组合疗法中的潜力.
主要成果:
- 水凝药物递送越来越多地结合了针对性行动的触发响应机制.
- 开发具有改进的机械性能,生物相容性和持续释放配置文件的先进水凝.
- 对纳米水凝和功能化材料的兴趣越来越大,以提高药物加载和有针对性的输送.
结论:
- 聚合物水凝正在迅速演变为复杂的药物输送系统,具有量身定制的特性.
- 未来的应用包括个性化医疗,多药物输送和组合疗法,有望提高治疗效率和降低成本.
- 水凝技术的持续创新将推动更高效,更有针对性的治疗策略.
相关概念视频
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Enteral delivery involves administering drugs directly through swallowing, sublingual placement, or buccal application. Orally administered drugs predominantly navigate the gastrointestinal...
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01:19Modified-Release Drug Delivery Systems: Rate-Programmed II
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01:23Modified-Release Drug Delivery Systems: Classification
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01:30Modified-Release Drug Delivery Systems: Stimuli-Activated
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01:24Site-Targeted Drug Delivery Systems: Polymeric Carriers
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01:11Oral Drug Delivery Systems: Delayed-Release Systems
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