坎迪达棕球菌:巴西的新兴威胁?
Gisela Lara da Costa1, Melyssa Negri2, Rodrigo Prado Rodrigues de Miranda1,3
1Laboratory of Taxonomy, Biochemistry and Bioprospecting of Fungi, Oswaldo Cruz Institution (IOC), Oswaldo Cruz Foundation (Fiocruz), Rio de Janeiro 21040-900, Brazil.
Journal of fungi (Basel, Switzerland)
|July 28, 2023
概括
气候变化和COVID-19大流行可能会促进新的真菌病. 研究人员在巴西的污水中发现了 *Candida palmioleophila*,这表明由于温度上升和毒性因素,它是潜在的新兴病原体.
科学领域:
- 环境微生物学环境微生物学
- 医学真菌学 医学真菌学
- 气候变化影响气候变化的影响.
背景情况:
- 气候变化改变了大气组成,造成了环境压力,可能引发新的真菌病.
- COVID-19 流行病已与真菌病原体的出现有关.
- 在高温下真菌的有限生长限制了哺乳动物的感染,但热耐受性发展是一个问题.
研究的目的:
- 在原始污水样本中检测和识别 *Candida palmioleophila*.
- 评估 *Candida palmioleophila* 的毒性因子,包括生物膜形成和酶生产.
- 评估 *Candida palmioleophila* 作为巴西新兴病原体的潜力,特别是在大流行期间.
主要方法:
- 多相分类学用于物种识别.
- 评估了诸如生物膜形成等病毒性方面.
- 评估了细胞外酶的产生.
主要成果:
- 在巴西Niteroi市的污水样本中成功检测和识别了*Candida palmioleophila*分离物.
- 该研究评估了已识别的分离物的关键毒性因素.
- 数据表明, *Candida palmioleophila* 具有潜在新兴病原体的特征.
结论:
- 在巴西的城市环境中发现了 *Candida palmioleophila*.
- 该物种表现出与致病性相关的毒性因素.
- 这些发现突出了 *Candida palmioleophila *作为巴西潜在的新兴真菌病原体,特别是在气候变化和COVID-19大流行的情况下.
相关概念视频
01:28Fungal Phylum Microsporidia
41
Microsporidia are a group of obligate intracellular fungi that were initially classified as protists but were later reclassified based on phylogenetic, molecular, and structural evidence linking them to the Chytridiomycota. These unicellular, non-motile organisms are highly specialized parasites that infect a wide range of animal hosts, including humans. They have evolved extensive genomic and metabolic reductions, making them highly dependent on their hosts for survival.Morphology and Genomic...
41
01:27Diversity of Protists II
48
Alveolates are a group of organisms recognized by the presence of alveoli, which are cytoplasmic sacs located beneath the cell membrane. While their function remains uncertain, alveoli may help regulate water balance by controlling how much water enters and leaves the cell. In dinoflagellates, these structures may serve as armor plates. There are three major types of alveolates: ciliates, which move using cilia; dinoflagellates, which use flagella for movement; and apicomplexans, which are...
48
01:50Threats to Biodiversity
22.4K
There have been five major extinction events throughout geological history, resulting in the elimination of biodiversity, followed by a rebound of species that adapted to the new conditions. In the current geological epoch, the Holocene, there is a sixth extinction event in progress. This mass extinction has been attributed to human activities and is thus provisionally called the Anthropocene. In 2019 the human population reached 7.7 billion people and is projected to comprise 10 billion by...
22.4K
01:28Fungal Phylum Ascomycota
42
Phylum Ascomycota, a major division within the subkingdom Dikarya, comprises a diverse range of fungal species, including both unicellular yeasts and filamentous molds such as Aspergillus and Penicillium. These fungi thrive in a variety of habitats, from aquatic ecosystems to terrestrial environments, playing crucial ecological and economic roles.Morphology and ReproductionThe defining characteristic of Ascomycetes, commonly referred to as sac fungi, is the ascus—a sac-like structure that...
42
01:29Biofilms
57
Biofilms are complex communities of microorganisms encased in a self-produced extracellular polysaccharide matrix attached to surfaces. These microbial consortia can include single or multiple species, providing enhanced survival benefits by forming organized, multilayered structures.The formation of biofilms occurs through four key stages: attachment, colonization, development, and dispersal.During attachment, free-swimming planktonic cells adhere to a surface, often facilitated by...
57
01:26Fungal Phylum Basidiomycota
125
Basidiomycota is a diverse phylum of fungi that includes ecologically significant decomposers such as white rot fungi, symbionts like mycorrhizal fungi, plant pathogens such as rusts and smuts, and edible species like Agaricus bisporus (the common button mushroom). These fungi play crucial roles in nutrient cycling, symbiotic relationships, and even human health. Their defining feature is the basidium, a microscopic club-shaped structure responsible for producing basidiospores.Fruiting Bodies...
125