用于骨再生的热处理骨灰的物理化学表征
Fatimah Suhaily Abdul Rahman1, Abdul Manaf Abdullah2, Asanah Radhi3
1School of Dental Sciences, Health Campus, Universiti Sains Malaysia, Kubang Kerian 16150, Kelantan, Malaysia.
Journal of functional biomaterials
|July 28, 2023
概括
在实验室中产生的骨灰 (GBA) 具有与商业GBA相似的特性. 这项研究为在骨再生应用中使用GBA铺平了道路.
科学领域:
- 生物材料科学 生物材料科学
- 材料工程 材料工程 材料工程
- 整形外科 整形外科 整形外科
背景情况:
- 骨富含酸,传统上用于骨折治疗.
- 酸对于骨再生过程至关重要.
研究的目的:
- 从传统方法扩大骨灰 (GBA) 生产规模,到实验室环境.
- 描述和比较实验室GBA (SGBA) 与商业GBA (CGBA) 的物理化学和形态特性.
主要方法:
- 热处理 (300°C和900°C的化) 和机械方法用于GBA生产.
- 包括FT-IR,XRF,XRD,EDX和FESEM在内的特征技术.
- 分析重点是物理化学性质,矿物学阶段,Ca/P比率和形态学.
主要成果:
- 在300°C处理后的SGBA表现出与CGBA相似的物理化学特性.
- 更高的加工温度减少了有机化合物和增加了结晶性.
- 在900°C下烧结的SGBA显示出酸的存在,Ca/P原子比为1.64,接近理想的1.67.
结论:
- 实验室规模的GBA生产是可行的,其性能与商业来源相比较.
- 温度显著影响GBA的有机含量和结晶性.
- 这些发现支持对GBA用于骨再生的进一步研究,重点关注生物特性.
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