活跃和缓解的格雷夫斯病患者的维生素D水平
Natapon Rattanamusik1, Suriyon Uitrakul2, Atchara Charoenpiriya1
1Department of Medicine, Maharaj Nakhon Si Thammarat Hospital, Nakhon Si Thammarat 80000, Thailand.
Medicines (Basel, Switzerland)
|July 28, 2023
概括
与缓解期患者相比,活跃的格雷夫斯病 (GD) 患者的维生素D水平较低,缺乏率更高. 维生素D水平与GD患者的自由T4负相关.
科学领域:
- 内分泌学 在内分泌学.
- 营养科学 营养科学
背景情况:
- 格雷夫斯病 (GD) 与维生素D水平的关联是有争议的.
- 跨GD阶段的维生素D差异尚未得到充分研究.
研究的目的:
- 比较维生素D水平在活跃与缓解的GD.
- 在GD患者中确定影响维生素D的因素.
主要方法:
- 75名GD患者 (活跃/缓解) 的横截面研究 (2021年).
- 收集的人口,临床和维生素D数据.
- 使用曼-惠特尼U和Chi-square测试进行分析.
主要成果:
- 活跃的GD组的维生素D平均水平较低 (28.23 ng/mL) 与缓解 (31.58 ng/mL).
- 维生素D缺乏 (<20 ng/mL) 在活跃的GD中为14.6%,缓解期为0% (p=0.02).
- 在维生素D和自由T4之间发现了负相关性 (p=0.03).
结论:
- 活跃的GD患者表现出较低的维生素D水平.
- 在活跃的GD中显著增加维生素D缺乏的患病率.
- 血清维生素D与GD中的血清自由T4负相关.
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