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在卵巢癌中,饥饿失活的MTOR通过ULK1-SH3PXD2A/TKS5-MMP14途径触发细胞迁移

Chiao-Yun Lin1, Kai-Yun Wu1,2, Lang-Ming Chi3

  • 1Gynecologic Cancer Research Center, Chang Gung Memorial Hospital, Taoyuan City, Guishan District, Taiwan.

Autophagy
|July 28, 2023
PubMed
概括

这项研究表明,SH3和PX域2A (SH3PXD2A/TKS5) 蛋白对于自开始至关重要. 它与unc-51直接相互作用,就像自细胞激活激酶1 (ULK1) 一样,促进自细胞形成.

关键词:
在MMP14中,MMP14是MMP14中的一个.这就是SH3PXD2A.ULK1 是一个ULK1细胞迁移 细胞迁移卵巢癌是发生在卵巢的癌症.

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