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完整的脱血疗法对乳腺癌的影响与淋巴胀有关:随机对照试验的系统性审查和元分析
Shaimaa Shamoun1, Muayyad Ahmad1
1School of Nursing, University of Jordan, Amman, Jordan.
Asian Pacific journal of cancer prevention : APJCP
|July 28, 2023
概括
建议对与乳腺癌相关的淋巴 (BCRL) 进行全方位脱血疗法 (CDT). 虽然有证据表明对生活质量,疼痛和有好处,但需要进一步的研究来证实有效性.
科学领域:
- 在瘤学瘤学.
- 物理疗法物理治疗
- 淋巴 edem 管理 淋巴 edem 管理
背景情况:
- 乳腺癌幸存者经常经历淋巴,这是一个慢性疾病,其特点是液体积累.
- 与乳腺癌相关的淋巴 (BCRL) 显著影响患者的生活质量,导致疼痛和移动性问题.
研究的目的:
- 批判性地分析现有关于完整脱血疗法 (CDT) 对管理BCRL的有效性的证据.
- 评估CDT对BCRL患者的生活质量,疼痛,运动范围 (ROM) 和的影响.
主要方法:
- 随机对照试验 (RCT) 的系统审查使用了PubMed,Google Scholar和EBSCO主机等主要数据库进行.
- 在分析了3,181篇文章后,包括了15个RCT,使用Jadad尺度评估质量,使用Cochrane Rob2工具评估偏差风险.
- 包括生活质量 (QOL),疼痛,ROM和等关键结果被提取和分析.
主要成果:
- 包含的研究具有很高的方法质量,提供了很好的证据.
- CDT显示了对QOL (2.347) 的积极影响大小,但没有达到统计显著性 (p=0.22).
- 对于疼痛 (-0.068,p=0.64),ROM (0.324,p=0.41) 或 (-2.9),没有发现显著的影响,尽管趋势表明潜在的益处.
结论:
- CDT仍然是BCRL的主要,实用的和具有成本效益的治疗建议.
- 鼓励患者使用CDT,以潜在地改善QOL,ROM,并减少疼痛和.
- 需要进一步进行高质量的研究,采用更大的样本大小,更长的随访时间和客观的结果措施,以加强BCRL中CDT的证据基础.
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