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Updated: Jul 21, 2025

Identifying the Effects of BRCA1 Mutations on Homologous Recombination using Cells that Express Endogenous Wild-type BRCA1
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Identifying the Effects of BRCA1 Mutations on Homologous Recombination using Cells that Express Endogenous Wild-type BRCA1

Published on: February 17, 2011

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可能的HLA类I和II类对由单个生殖系BRCA1突变驱动的恶性瘤的影响

Milena Ivanova1, Anastasia Ormandjieva1, Rumyana Dodova2

  • 1Department of Clinical Immunology, University Hospital Alexandrovska, Medical University Sofia, Sofia, Bulgaria.

International journal of immunogenetics
|July 28, 2023
PubMed
概括

这项研究揭示了特定的人类白细胞抗原 (HLA) 类型和与BRCA1相关的癌症发展之间的联系. 这些发现可能有助于预测患者对免疫疗法治疗的反应.

关键词:
这是一种BCRA1突变.HLA 一级的I类.在HLAII类中,HLA是II类.乳腺癌 乳腺癌 乳腺癌卵巢癌是发生在卵巢的癌症.

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