身体成分对SARS-Cov-2感染后患者预后的影响
Takayuki Yamamoto1, Kazushi Sugimoto2, Syuhei Ichikawa1
1Department of General Medicine, Mie University Hospital, Tsu, Japan.
PloS one
|July 28, 2023
概括
高肌肉内脂肪组织含量 (IMAC) 可能预测非肥胖个体的2019年冠状病毒严重疾病 (COVID-19). 这种体质成分指标不能预测肥胖患者的严重程度或死亡率.
科学领域:
- 医疗成像医学成像
- 放射学 放射学是一门学科.
- 传染性疾病 传染性疾病
背景情况:
- 冠状病毒疾病2019 (COVID-19) 严重程度与高血压,糖尿病和肥胖等因素有关.
- 身体组成和COVID-19预后之间的特定关系需要进一步调查.
研究的目的:
- 调查身体组成参数与COVID-19严重程度之间的关联.
- 为了确定身体组成指标是否可以预测COVID-19患者的严重疾病过程或死亡率.
主要方法:
- 分析了76名COVID-19患者的计算机断层扫描 (CT) 扫描.
- 测量了身体组成指标,包括内脏脂肪面积 (VFA),psoas肌肉面积 (PMA),psoas肌肉质量指数 (PMI) 和肌肉内脂肪组织含量 (IMAC).
- 根据疾病的进展,患者被分为严重 (需要输管/通风) 或不严重.
主要成果:
- 严重的COVID-19病例与不严重的病例相比,体重,BMI和VFA都较高.
- 这些参数 (体重,BMI,VFA) 与疾病死亡率没有相关性.
- 在非肥胖组中,在严重病例中观察到更高的IMAC.
结论:
- 升高的IMAC可能成为非肥胖的日本患者中严重COVID-19的预测因素.
- IMAC没有预测肥胖患者的疾病严重程度或任何肥胖等级的死亡率.
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