对于结肠恶性病的结肠切除术后,长期肠道功能是否会发生变化?
Phillip J Gray1, Amanda J Bastien1, Mark A Eid1
1Department of Surgery, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire; Geisel School of Medicine, Hanover, New Hampshire.
The Journal of surgical research
|July 28, 2023
概括
结肠癌的长期切除术可以改善便相关的症状,如疼痛和出血. 这项研究评估了手术后患者报告的肠功能变化,为手术前咨询提供了洞察力.
科学领域:
- 结肠直肠外科手术是什么意思
- 在瘤学瘤学.
- 患者报告的结果.
背景情况:
- 了解结肠癌结肠切除术后的肠功能对于患者咨询至关重要.
- 以前的研究表明,肠道排便频率的短期增加,但没有整体功能变化.
- 切除术后的长期功能变化在很大程度上是未知的.
研究的目的:
- 为了评估患者报告的结肠功能在结肠癌的结肠切除术后的长期变化.
主要方法:
- 一项观察性研究,涉及因结肠癌而接受大肠切除术的患者.
- 在手术前和长期随访 (中位数为16个月) 中使用结肠直肠功能结果 (COREFO) 问卷.
- 使用患者报告结果测量信息系统-10 (PROMIS-10) 评估生活质量.
主要成果:
- 66名患者完成了这项研究.
- 在便相关方面观察到显著改善,包括疼痛,出血和门皮肤刺激.
- 在其他COREFO领域或总分数中没有发现任何重大变化.
- PROMIS-10评分表明生活质量与美国普通人口相美.
结论:
- 结肠癌的结肠切除术导致特定便相关症状的长期改善.
- 这些发现应纳入基于证据的手术前患者咨询.
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