相关实验视频

Updated: Jul 21, 2025

Strand-Specific Analysis of Proteins at Replicating DNA Strands by Enrichment and Sequencing of Protein-Associated Nascent DNA Method
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Strand-Specific Analysis of Proteins at Replicating DNA Strands by Enrichment and Sequencing of Protein-Associated Nascent DNA Method

Published on: May 2, 2025

419

波尔α-原酶是如何向复制体的,以促进真核细胞DNA复制的

Morgan L Jones1, Valentina Aria1, Yasemin Baris1

  • 1MRC Laboratory of Molecular Biology, Cambridge CB2 0QH, UK.

Molecular cell
|July 28, 2023
PubMed
概括

DNA复制依赖于Pol α-原酶来创建原始体. 新的冷EM结构揭示了Pol α-原酶直接与CMG基酶结合,协调DNA在复制分叉中的原始化.

关键词:
在CMG中,CMG是CMG.DNA聚合酶是一种DNA聚合酶.复制DNA复制DNA复制DNA复制聚α-原酶是一种低温电磁冷却仪的使用方法基因组稳定性的基因组稳定性螺旋酸的使用方法启动初始化 启动一些重复的重复.

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