将神经系统疾病与生殖内分泌功能障碍联系在一起的机制:来自研究的见解
Cathryn A Cutia1, Catherine A Christian-Hinman2
1Neuroscience Program, University of Illinois Urbana-Champaign, Urbana, IL, USA.
Frontiers in neuroendocrinology
|July 28, 2023
概括
阴道激素会影响大脑疾病,会显示出生殖内分泌功能障碍. 本综述探讨了发作如何影响下丘脑-垂体-腺轴以及荷尔蒙如何影响发作活动.
科学领域:
- 神经内分泌学神经内分泌学
- 的研究研究.
- 生殖内分泌学 生殖内分泌学
背景情况:
- 淋巴腺激素会影响神经系统疾病的症状.
- 经常与生殖内分泌功能障碍 (RED) 一起发生.
- 在下丘脑-垂体-腺 (HPG) 轴和等神经系统疾病之间存在相互相互作用.
研究的目的:
- 审查关于发作和HPG轴功能障碍之间的联系的临床和临床前证据.
- 描述HPG轴荷尔蒙如何影响发作活动.
- 探索神经系统疾病和HPG轴功能障碍之间的联系机制.
主要方法:
- 临床数据的审查.
- 对临床前动物模型的分析.
- 综合现有关于和神经内分泌学的文献.
主要成果:
- 发作可以破坏HPG轴.
- HPG轴荷尔蒙可以调节发作值和活动.
- 发作和RED之间的机制联系尚未完全理解.
结论:
- 的研究提供了关于神经系统疾病中HPG轴功能障碍的见解.
- 了解这些相互作用对于神经内分泌学至关重要.
- 需要进一步调查以阐明涉及的机制.
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