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PARP14是单一ADP-ribosylation的写入器,读取器和擦除器

Archimede Torretta1, Constantinos Chatzicharalampous1, Carmen Ebenwaldner1

  • 1Department of Chemistry, Center for Molecular Protein Science (CMPS), Lund University, Lund, Sweden.

The Journal of biological chemistry
|July 28, 2023
PubMed
概括

研究人员描述了PARP14的宏观体-1并发现它具有类似于PARP9.9的ADP-ribosyl glycohydrolase活性. 这一发现影响了对PARP14和PARP9在疾病和治疗中的作用的理解.

关键词:
在ADP-ribosylation过程中.它们是ADP-ribosyl转移酶.酶酸盐的使用方法宏观领域是一个宏观领域.聚基聚合酶 (PARP) 是一种聚基聚基聚合酶 (PARP).后翻译修改 (PTM) 是一种后翻译修改.蛋白质领域 蛋白质领域信号传输 信号传输

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