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性细胞内pH值 (pHi) 增加PI3K活动,促进mTORC1和mTORC2信号传递和生长因子限制期间的功能

Dubek Kazyken1, Stephen I Lentz2, Maxwell Wadley1

  • 1Department of Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor, Michigan, USA.

The Journal of biological chemistry
|July 28, 2023
PubMed
概括

性细胞内pH值激活PI3K-mTOR信号,通过模仿生长因子信号来促进癌细胞的生长和生存. 这一发现揭示了在营养压力下癌细胞增殖的关键机制.

关键词:
这就是Akt PKB的PKB.在PI3K中,PI3K是指PI3K.这就是S6酶.灭症 (apoptosis) 是一种死亡的过程.细胞信号传递是细胞的信号传递.单核细胞翻译启动因子4E细胞转化启动因子4E结合蛋白质调节pH值的方法蛋白质合成 蛋白质合成拉帕米的目标是拉帕米.

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