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Updated: Jul 21, 2025

Using the E1A Minigene Tool to Study mRNA Splicing Changes
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替代拼接调节了在神经元发育中的Vps10p域受体SorCS2的适配蛋白结合,贩运和活性

Sune Skeldal1, Lasse Frank Voss1, Jonas Lende1

  • 1Department of Biomedicine, Aarhus University, Aarhus C, Denmark.

The Journal of biological chemistry
|July 28, 2023
PubMed
概括

这项研究揭示了八种SorCS2蛋白质异型,由四种拼接变体生成,可以差异调节神经元可塑性和贩运. 这些异构体与特定的运动蛋白相互作用,影响来自大脑的神经营养因子 (BDNF) 信号传递.

关键词:
这就是为什么BDNF是BDNF.在SorCS2中使用.替代性拼接是一种替代性的拼接.细胞的压力是细胞的压力.这就是Dynein.在中国,中国就是中国.接收器贩运 接收器贩运 接收器贩运

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