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Updated: Jul 21, 2025

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人类Cdc123与eIF2γ的结合

Cristina Cardenal Peralta1, Paul Vandroux1, Lea Neumann-Arnold2

  • 1Laboratoire de Biologie Structurale de la Cellule, BIOC, Ecole polytechnique, CNRS, Institut Polytechnique de Paris, 91128 Palaiseau cedex, France.

Journal of structural biology
|July 28, 2023
PubMed
概括

Cdc123蛋白质结构揭示了它如何帮助真核细胞启动因子2 (eIF2) 组合,这对蛋白质合成至关重要. 在eIF2组合中,ATP结合对Cdc123功能至关重要,影响了MEHMO综合征等疾病.

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