如何减少对有多种长期疾病的人的药物
Helen Saul1, Samantha Cassidy1, Brendan Deeney1
1NIHR Evidence, Twickenham, UK.
BMJ (Clinical research ed.)
|July 28, 2023
概括
对于有多种健康状况和多种药物的老年人来说,停止处方药物可以安全地完成. 泰勒的证据综合提供了指导在这个人群中抑郁症的指导.
科学领域:
- 老年医学 老年医学
- 临床药房 临床药房
- 证据综合 证据综合
背景情况:
- 老年人经常有多种慢性疾病 (多重病变).
- 多药性,即定期使用多种药物,在这个群体中很常见.
- 在多重疾病的老年人中,管理多种药物存在重大挑战.
研究的目的:
- 综合有关老年人多病症和多药性抑郁症药物处方的证据.
- 提供关于药物的安全和有效减产处方的指导.
- 支持医疗保健专业人员为这一群体优化药物治疗方案.
主要方法:
- 系统的文献审查和证据综合.
- 分析相关临床试验和观察性研究的数据.
- 开发基于证据的建议,以减少处方.
主要成果:
- 确定了安全降低药物使用的策略和干预措施.
- 突出了抑郁症的潜在好处,包括减少不良事件.
- 提供了一个评估老年人多病症药物适宜性的框架.
结论:
- 降低处方对具有多病症和多药性的老年人来说是可行的和有益的.
- 一种结构化,基于证据的方法对于安全的抑郁症至关重要.
- 实施抑郁症的策略可以改善患者的治疗结果,并减少药物负担.
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