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A Doxorubicin-Induced Murine Model of Dilated Cardiomyopathy In Vivo
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心脏磁性放松计与射分数在与环素有关的心脏变化:一个系统性审查和元分析
Christopher Yu1,2, Shahab Pathan2,3, Prajith Jeyaprakash1,2
1Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia.
Open heart
|July 28, 2023
概括
这一元分析发现了心磁共振 (CMR) 成像参数的小但显著的变化,包括细胞外体积 (ECV),左心室射出分数 (LVEF),T1和T2映射,在环素化疗后不久. 在检测这些早期心脏变化方面,ECV显示出优越性.
科学领域:
- 心脏病学 心脏病学
- 在瘤学瘤学.
- 放射学 放射学是一门学科.
背景情况:
- 人环素可以导致心肌损伤,影响心脏功能和结构.
- 左心室喷射分数 (LVEF) 是功能变化的标准衡量标准.
- 心脏磁共振 (CMR) 放松计技术 (T1/T2映射,ECV) 可以检测炎症和.
结论:
- 在CMR放松计参数显示,在环素治疗后发生了小但显著的变化.
- 细胞外体积 (ECV) 在检测这些短期变化方面表现出优于LVEF,T1和T2映射的优势.
- 观察到的短期变化低于最小可检测差异,这表明使用先进技术更早检测的可能性.
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