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使用可穿戴活动监视器测量骨淋巴结解剖和哨兵淋巴结活检后的上肢身体活动
Nur Amalina Che Bakri1,2, Richard M Kwasnicki3,4, Emmanuel Giannas3
1Department of Surgery and Cancer, Imperial College London, London, UK. nchebakr@ic.ac.uk.
Annals of surgical oncology
|July 28, 2023
概括
在乳腺癌患者中,手臂淋巴结解剖 (ALND) 显著减少身体活动 (PA),远远超过哨兵淋巴结活检 (SLNB). 此外,SLNB还显示了对PA的长期影响,强调了客观恢复监测的必要性.
科学领域:
- 在瘤学瘤学.
- 术后恢复 术后恢复
- 生物医学工程 生物医学工程
背景情况:
- 从哨兵淋巴结活检 (SLNB) 和带淋巴结剖析 (ALND) 的发病率被不充分评估.
- 目前的评估方法是主观的,容易产生偏见.
- 可穿戴活动监测器 (WAM) 为恢复评估提供了对身体活动 (PA) 的客观,定量分析.
研究的目的:
- 客观地评估和比较SLNB和ALND对患者身体活动和康复的影响.
- 探索可穿戴活动监测器 (WAM) 在评估外科手术结果方面的潜力.
- 提供证据,证明潜在的关缓和策略.
主要方法:
- 前性,单中心观察性研究 (2020年2月 - 2022年5月).
- 56名乳腺癌患者被招募,35名接受SLNB,21名接受ALND.
- 患者在手术前3天和手术后2周佩戴WAM,以测量PA.
主要成果:
- 与SLNB患者相比,ALND患者在第2周的PA显著降低 (中位数为66.4%与72.7%,p=0.015).
- 亚组分析:简单的乳房切除术 (Mx) -ALND在第2周的PA低于Mx-SLNB (中位数为90.3%与70.5%,p=0.015).
- 在手术后2周内,SLNB的PA并没有恢复到基线.
结论:
- 与SLNB相比,ALND在手术后2周导致明显较低的PA.
- 此外,SLNB对PA也有长期的影响,持续超过2周.
- 使用WAM的客观恢复监测可以为个性化康复计划和手术决策提供信息.
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