一种新型四烯酸化合物作为潜在的抗氧化剂的合成,表征和评估
Mengqi Xu1,2, Pengcheng Meng1, Hongyan Wang3
1College of Food Science and Technology, Henan University of Technology, Zhengzhou 450001, China.
Antioxidants (Basel, Switzerland)
|July 29, 2023
概括
合成了一种新的抗氧化剂,即2,2' - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - 甲基-1,3-二) 双 (MPBHQ),与现有的抗氧化剂相比,它在脂质和生物柴油中表现出更优的激素清除和氧化稳定性.
科学领域:
- 有机化学 有机化学
- 聚合物科学 聚合物科学
- 食品化学 食品化学
背景情况:
- 氧化降解会影响脂质和生物柴油的稳定性和保质期.
- 现有的合成抗氧化剂如BHT和TBHQ面临着严格的审查和限制.
- 持续需要新型抗氧化剂,其疗效和安全性有所提高.
研究的目的:
- 为了合成和描述一种新型抗氧化剂,2,2' - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - 甲基-1,3-二) 双 (MPBHQ) 的特性.
- 评估MPBHQ的激素清除活性和抗氧化性能.
- 为了比较MPBHQ对脂质和生物柴油矩阵中已确定的抗氧化剂的疗效.
主要方法:
- 使用基和甲基醇与酸催化剂合成MPBHQ.
- 通过质谱学,NMR,UV和IR光谱学进行结构性表征.
- 使用ORAC,DPPH,ABST测定和Rancimat测试进行抗氧化活性评估.
主要成果:
- MPBHQ已成功合成并结构确认.
- 在多个测试中,MPBHQ表现出显著的激进清理能力.
- 在脂肪酸甲基和油脂中,MPBHQ在脂肪酸甲基和油脂中表现出比BHT,HQ,TBHQ和PG更好的抗氧化性能.
结论:
- MPBHQ是一种有前途的新型抗氧化剂,具有强大的激素清除特性.
- 与传统抗氧化剂相比,MPBHQ为脂质和生物柴油提供了增强的氧化稳定性.
- MPBHQ满足了对新的抗氧化剂的需求,并提高了工业应用的性能.
相关概念视频
Oxidation of Phenols to Quinones
3.1K
In the presence of oxidizing agents, phenols are oxidized to quinones. Quinones can be easily reduced back to phenols using mild reducing agents. The electron-donating hydroxyl group enhances the reactivity of the aromatic ring, enabling oxidation of the ring even in the absence of an α hydrogen.
o-hydroxy phenols are oxidized to o-quinones and p-hydroxy phenols to p-quinones. Such redox reactions involve the transfer of two electrons and two protons. The reversible redox...
o-hydroxy phenols are oxidized to o-quinones and p-hydroxy phenols to p-quinones. Such redox reactions involve the transfer of two electrons and two protons. The reversible redox...
3.1K
Radical Autoxidation
2.2K
The oxidation of an organic compound in the presence of air or oxygen is called autoxidation. For example, cumene reacts with oxygen to form hydroperoxide. Autoxidation involves initiation, propagation, and termination steps. Many organic compounds are susceptible to autoxidation—especially ethers in the presence of oxygen, which form hydroperoxides. Even though this reaction is slow, old ether bottles contain small amounts of peroxide, which leads to laboratory explosions during ether...
2.2K
Aromatic Hydrocarbon Cations: Structural Overview
2.9K
Cycloheptatriene is a neutral monocyclic unsaturated hydrocarbon that consists of an odd number of carbon atoms and an intervening sp3 carbon in the ring. The three double bonds in the ring correspond to 6 π electrons, which is a Huckel number, and therefore satisfies the criteria of 4n + 2 π electrons. However, the intervening sp3 carbon disrupts the continuous overlap of p orbitals. As a result, cycloheptatriene is not aromatic.
Removing one hydrogen from the intervening CH2 group...
Removing one hydrogen from the intervening CH2 group...
2.9K
Radical Chain-Growth Polymerization: Overview
2.5K
Chain-growth or addition polymerization is successive addition reactions of monomers with a polymer chain. In radical chain-growth polymerization, the reaction proceeds via a free-radical intermediate. The free radical is formed from radical initiators, which spontaneously generate free radicals by homolytic fission. Organic peroxides (such as dibenzoyl peroxide, as shown in Figure 1) or azo compounds are popular radical initiators. A low concentration ratio of radical initiator to monomer is...
2.5K
ortho–para-Directing Activators: –CH3, –OH, –⁠NH2, –OCH3
6.1K
All ortho–para directors, excluding halogens, are activating groups. These groups donate electrons to the ring, making the ring carbons electron-rich. Consequently, the reactivity of the aromatic ring towards electrophilic substitution increases. For instance, the nitration of anisole is about 10,000 times faster than the nitration of benzene. The electron-donating effect of the methoxy group in anisole activates the ortho and para positions on the ring and stabilizes the corresponding...
6.1K


