五种商用精油不同样本的抗菌和抗生物膜作用
Răzvan Neagu1,2, Violeta Popovici3, Lucia Elena Ionescu4
1Department of Pharmacognosy, Phytochemistry, and Phytotherapy, Faculty of Pharmacy, Carol Davila University of Medicine and Pharmacy, 6 Traian Vuia Street, 020956 Bucharest, Romania.
Antibiotics (Basel, Switzerland)
|July 29, 2023
概括
商用精油表现出不同的抗菌和抗菌膜活性. 化学成分,采购和加工的差异影响了对黄金菌和大肠杆菌等细菌的疗效.
科学领域:
- 微生物学 微生物学
- 自然产品 化学 化学
背景情况:
- 精油 (EOs) 对于其生物活动的需求越来越大,但来自不同供应商的样品之间存在显著差异.
- 公司和在线销售的激增导致EO质量和有效性的不一致.
研究的目的:
- 研究商用精油的抗菌和抗菌膜活性.
- 为了比较俄里加诺,欧卡利普斯,迷香,花和胡油对格拉姆阳性 (金黄色葡萄球菌) 和格拉姆阴性细菌 (大肠杆菌, Pseudomonas aeruginosa) 的疗效.
主要方法:
- 使用气体染色学-质谱学 (GC-MS) 分析化学成分.
- 使用微板培养技术对抗菌和抗菌膜效应 (ABE%和ABfE%) 的体外评估.
- 在562和570nm的光谱测量.
- 与标准抗生素的比较 (阿莫西西林/克拉夫兰酸,仁氨酸,链氨酸).
主要成果:
- 所有测试的EO在初始稀释 (25 mg/mL) 时都显示出对所有测试细菌的抗菌和抗菌膜活性.
- 随着稀释,活性总体上下降;大肠杆菌表现出最低的敏感性.
- 胡卜和花生油在化学成分和生物活性方面表现出最显著的差异.
- 差异归因于原材料采购,加工和储存等因素.
结论:
- 商用精油在其抗菌和抗菌膜性质上表现出相当大的变化.
- 生产和质量控制的标准化对于一致的EO疗效至关重要.
- 需要进一步的研究来了解影响EO生物活性的复杂相互作用.
关键词:
丁香油是指甲油的一种.树油 树油的使用里加诺油是菜油的一种.胡香精油油的使用方法迷香油:迷香油的使用方法它具有抗菌活性,具有抗菌活性.抗菌膜效应的抗菌膜效应生物活性成分 生物活性成分主要组件分析的主要组件分析更多相关视频
09:07The Effect of the Application of Thyme Essential Oil on Microbial Load During Meat Drying
Published on: March 14, 2018
9.6K
08:20Systematic Approach to Identify Novel Antimicrobial and Antibiofilm Molecules from Plants' Extracts and Fractions to Prevent Dental Caries
Published on: March 31, 2021
6.4K
相关概念视频
01:28Antimicrobial Effectiveness
48
The effectiveness of antimicrobial agents depends on various factors influencing their ability to eliminate microbial populations. Larger microbial populations require more time for complete eradication, emphasizing the importance of population size analysis when evaluating antimicrobial efficacy.Microbial resistance to antimicrobial agents varies significantly. Highly resilient microorganisms include endospores, gram-negative bacteria, and non-enveloped viruses, while prions are exceptionally...
48
01:18Surface Membrane Barriers
1.2K
The skin and mucous membranes serve as the primary line of defense against pathogens by providing both physical and chemical protection. These barriers are essential in preventing the entry and establishment of microbes, thereby maintaining the integrity of the host.
The outer layer of the skin, the epidermis, is a robust barrier comprising layers of closely packed keratinized cells. This dense arrangement prevents microbes from penetrating the body. The periodic shedding of epidermal cells...
The outer layer of the skin, the epidermis, is a robust barrier comprising layers of closely packed keratinized cells. This dense arrangement prevents microbes from penetrating the body. The periodic shedding of epidermal cells...
1.2K
01:27Chemical Agents for Microbial Control
54
Chemicals play important roles in controlling microbial growth by targeting microbial structures and functions as sanitizers, antiseptics, disinfectants, and sterilants.Alcohols are commonly used sanitizers, effectively disrupting lipid membranes, which compromises cell integrity. They are also used as antiseptics and disinfectants due to their rapid action and versatility.Phenols and their derivatives phenolics , known for denaturing proteins and disrupting cell membranes, are particularly...
54
01:28Biological Methods for Microbial Control
64
Biological agents offer an effective means of controlling microbial growth by leveraging natural processes like predation, competition, and the secretion of antimicrobial substances.Predatory bacteria such as Bdellovibrio species target and kill pathogens like Salmonella and E. coli. They are widely used in poultry farms to control infections. Myxococcus species help combat plant-pathogenic fungi. These naturally occurring predators serve as eco-friendly alternatives to chemical pesticides and...
64
01:29Biofilms
56
Biofilms are complex communities of microorganisms encased in a self-produced extracellular polysaccharide matrix attached to surfaces. These microbial consortia can include single or multiple species, providing enhanced survival benefits by forming organized, multilayered structures.The formation of biofilms occurs through four key stages: attachment, colonization, development, and dispersal.During attachment, free-swimming planktonic cells adhere to a surface, often facilitated by...
56
01:27Combined Effects of Drugs: Synergism
4.0K
Synergism is a useful mechanism where combining two or more drugs is more effective than each constituent used alone. Such combinations are also called supra-additive interactions. The drugs collectively enhance the final therapeutic effect by acting on different targets. Another advantage is that the low dose of each constituent drug is sufficient to achieve the desired effect. This helps reduce the duration of therapy and lower the adverse effects of these drugs.
Such synergistic combinations...
Such synergistic combinations...
4.0K