作为儿童年龄的新兴病原体:病例报告和系统审查
Claudia Colomba1,2, Valeria Garbo1, Giovanni Boncori1
1Department of Health Promotion, Maternal and Infant Care, Internal Medicine and Medical Specialties, University of Palermo, 90100 Palermo, Italy.
Antibiotics (Basel, Switzerland)
|July 29, 2023
概括
一种常见的口腔细菌Streptococcus mitis,即使在健康的儿童中,也可能导致严重的侵入性感染,如脑膜炎和脑中静脉血栓症. 这凸显了口腔卫生的重要性,以及由于新出现的耐药性,谨慎选择抗生素.
科学领域:
- 微生物学 微生物学
- 传染性疾病 传染性疾病
- 儿科 儿科 儿科
背景情况:
- 杆菌菌 (S. mitis) 是维里达斯群杆菌 (VGS) 的一种,通常在口腔中发现.
- 虽然通常被认为在免疫能力较强的人群中具有较低的致病性,但S. mitis可以引起侵袭性疾病,特别是在免疫功能低下的患者中.
研究的目的:
- 研究S.mitis在侵袭性感染中的病原性作用.
- 审查有关儿科患者侵袭性S. mitis疾病的文献.
- 突出口腔健康状况在侵袭性感染中的重要性.
主要方法:
- 一个以前健康的12岁男孩患有鼻炎,脑膜炎和由S. mitis引起的脑中静脉血栓 (CSVT) 的病例报告.
- 关于儿童群体侵入性S. mitis感染的广泛文献综述.
主要成果:
- 在免疫能力较强的儿童中,S. mitis可以引起严重的侵入性感染,包括脑膜炎和CSVT.
- 糟糕的口腔健康状况 (例如,鼻炎,) 可能是侵入性S. mitis感染的诱导因素.
- 在VGS中出现的抗菌素耐药性模式需要仔细考虑治疗选择.
结论:
- S.mitis在侵袭性感染中起着至关重要的作用,即使在具有易感性疾病的免疫能力强的儿童中也是如此.
- 保持良好的口腔卫生对于预防侵入性细菌感染至关重要.
- 对VGS抗微生物耐药性的认识对于有效的治疗策略至关重要.
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