呼吸道共囊病毒:对断层扫描结果的系统审查和元分析 (2000-2022)
Matteo Riccò1, Silvia Corrado2, Sara Palmieri3
1Local Health Unit of Reggio Emilia, Servizio di Prevenzione e Sicurezza Negli Ambienti di Lavoro (SPSAL), AUSL-IRCCS di Reggio Emilia, 42122 Reggio Emilia, Italy.
Children (Basel, Switzerland)
|July 29, 2023
概括
人类呼吸道同胞性病毒 (RSV) 导致大量婴儿住院,但胸部CT检测结果未得到充分研究. 这篇综述揭示了常见的CT特征,如组织性肺炎和隔膜加厚,成年人与儿童相比显示出不同的模式.
科学领域:
- 放射学 放射学是一门学科.
- 传染性疾病 传染性疾病
- 肺部病理学 肺部病理学
背景情况:
- 人类呼吸道同胞性病毒 (RSV) 是婴儿住院的主要原因之一.
- 有限的数据存在胸部计算机断层扫描 (CT) 在RSV感染的发现.
研究的目的:
- 系统地审查和综合有关RSV病例胸部CT特征的现有证据.
- 识别常见的CT发现并将其与不同年龄组和免疫状况进行比较.
主要方法:
- 按照PRISMA指南,在PubMed,Embase和medRxiv进行了系统的文献搜索,直到2022年12月.
- 包括观察性研究,并将病例分为儿童/青少年,成年人/老年人和免疫受损患者.
- 用一个随机效应模型汇集数据,评估异质性和偏差.
主要成果:
- 分析了10项研究,其中包括217例RSV病例.
- 常见的发现包括组织性肺炎 (33.65%),隔膜加厚 (33.19%),磨砂玻璃不透明 (GGOs; 28.03%),以及树 (TIB; 27.44%).
- 双边参与是常见的 (76.06%),16.23%的病例有正常的CT发现. 成年人与儿童相比, septal 加厚,结节性病变和 GGOs 的风险更高.
结论:
- 呈现异质CT特征的RSV感染,在儿科和成人群体之间有所不同.
- 特定的CT模式,如组织性肺炎和隔膜加厚是普遍存在的.
- 缺乏研究需要谨慎地解释研究结果,强调需要更多的研究.
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