复杂区域性疼痛综合征的处方趋势:一个回顾性病例对照研究
Suzanna Shermon1, Kimberly M Fazio1, Richard Shim2
1MetroHealth Medical Center, Case Western Reserve University, 4229 Pearl Road, Cleveland, OH 44109, USA.
Brain sciences
|July 29, 2023
概括
这项研究发现,与文献建议相比,复杂区域性疼痛综合征 (CRPS) 患者如何处方止痛药存在显著差异. 建议的治疗指南与CRPS管理的实际临床实践之间存在显著的分歧.
科学领域:
- 疼痛医学 医学 疼痛医学
- 药理学 药理学是指药理学的学科.
- 临床实践研究 临床实践研究
背景情况:
- 复杂区域性疼痛综合征 (CRPS) 提出了各种治疗方法的治疗挑战.
- 了解当前的处方模式对于使临床实践与基于证据的建议保持一致至关重要.
研究的目的:
- 评估复杂区域疼痛综合征 (CRPS) 患者的止痛药处方趋势.
- 为了确定基于文献的建议和实际的CRPS患者的处方实践之间的差异.
主要方法:
- 一项追溯病例控制研究,涉及2510名CRPS患者和2510名匹配对照.
- 分析了各种类别的止痛药 (如阿片类药物,神经病痛药,NSAID) 的处方数据.
- 电子健康记录被用来识别CRPS诊断和检索处方数据.
主要成果:
- 与对照人群相比,CRPS患者的服用类药物,素,神经性疼痛药物和阿片类药物的处方率明显较高.
- 在CRPS患者和对照组中,类固醇和NSAID处方率在CRPS患者和对照组中相似.
- 在CRPS患者 (59%) 与对照 (49%) 之间观察到阿片类药物处方的显著增加.
结论:
- 对CRPS患者的止痛药处方的临床实践偏离了一些既定的文献建议.
- 需要进一步的研究来协调处方模式与最佳的CRPS治疗策略.
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