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一种新的手术内测绘图装置检测了热力学响应函数

Michael Iorga¹, Nils Schneider¹, Jaden Cho¹

¹Department of Radiology, Feinberg School of Medicine, Chicago, IL 60611, USA.

|July 29, 2023

概括

红外热学可以通过检测手术期间的温度变化来绘制大脑活动的地图. 这项研究确定了一种特定的热冲动响应功能,提高了大脑绘图的准确性.

科学领域:

神经科学是一个神经科学.
医疗成像医学成像
手术技术手术技术

背景情况:

功能性大脑激活会增加局部温度和 perfusion.
红外热学可以在手术期间可视化皮质表面温度变化.
缺乏对这些热变化的定量空间时间分析.

研究的目的:

开发和验证一个新的手术内红外热学系统.
描述功能激活期间大脑的热冲动响应功能.
为了提高神经外科手术中的功能映射的准确性.

主要方法:

开发一种新的手术内红外热学装置和数据收集软件.
在6名接受清醒切除术的患者中进行了验证,并进行了运动和感官映射任务.
组主要组件分析,以确定皮层温度变化的共享时空模式.

主要成果:

在患者之间确定一致的热激活峰值.
热冲动响应函数的特征与5秒的开始延迟和10秒的峰值持续时间.
生成的功能地图显示与直接电刺激结果有很强的对应.

结论:

这项研究证明了以前未知的脉冲响应功能,用于使用手术内红外热学绘制的功能映射.
这种新的设备和分析为大脑绘图提供了更为定量化的方法.
这些发现对改善手术内神经外科指导有重大影响.

关键词:

大脑绘制地图功能神经成像功能神经成像图像引导的神经外科图像引导的神经外科红外热像学红外热像学红外热像学在手术内进行映射.

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