在患有单侧性脑麻的儿童中,受损的抓取功能的神经相关因子
Jennifer Gutterman1, Andrew M Gordon1
1Department of Biobehavioral Sciences, Teachers College, Columbia University, New York, NY 10027, USA.
Brain sciences
|July 29, 2023
概括
单边性脑 (USCP) 影响由于大脑发育损伤而导致的抓取能力. 本综述探讨了导致这些运动障碍的皮质脊髓管完整性和感官整合缺陷.
科学领域:
- 神经学 神经学
- 发育神经科学的发展神经科学.
- 康复科学 康复科学 康复科学
背景情况:
- 单侧性脑 (USCP) 是一种影响运动功能的发育障碍,主要影响身体的一侧.
- 患有USCP的儿童经常遇到难以抓住物体的困难,影响日常活动.
- 虽然运动功能是分类的关键,但感官异常常常存在并可能加剧抓住障碍.
研究的目的:
- 审查皮质脊柱管 (CST) 完整性和USCP中掌握控制之间的关系.
- 探索感官和感官运动整合缺陷对理解障碍的贡献.
- 突出研究方法来剖析感官运动相互作用的把握.
主要方法:
- 对USCP,抓取,皮质脊柱管和感官处理现有文献的综述.
- 对测量指尖力在对象操纵任务中的研究进行分析.
- 讨论研究检查感官和运动系统相互作用的研究.
主要成果:
- 皮质脊髓管 (CST) 完整性和连接性与抓取执行和预测控制相关.
- 感官和感官运动一体化缺陷在抓握障碍中起着重要作用,仅仅通过CST完整性无法完全解释.
- 在对象操纵过程中测量指尖力量有效地揭示了抓取感官和运动功能之间的相互作用.
结论:
- 无论是CST完整性还是感官/感官运动一体化,都对掌握USCP中的功能至关重要.
- 需要采用全面的方法,以互动的方式检查感觉和运动系统,以了解抓取障碍.
- 未来的研究应该集中在这些综合机制上,为USCP开发有针对性的干预措施.
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