术后通讯性水脑病在二/三级质瘤切除后:发生率,时间和危险因素
Lisa S Hönikl1, Nicole Lange1, Bernhard Meyer1
1Department of Neurosurgery, Klinikum Rechts der Isar, School of Medicine, Technical University of Munich, Ismaninger Str. 22, 81675 Munich, Germany.
Cancers
|July 29, 2023
概括
需要脑脊液 (CSF) 转移手术的沟通性水头 (CH) 在质瘤切除后发生在6.9%的患者中. 3级质瘤,再出血和腹腔炎是手术后发展CH的关键危险因素.
科学领域:
- 神经外科 神经外科
- 在瘤学瘤学.
- 神经病理学神经病理学
背景情况:
- 瘤切除的程度对于扩散性质瘤的生存至关重要.
- 在质母细胞瘤 (世卫组织4级) 切除后,诸如腹腔炎之类的并发症可能导致通讯性水头发炎 (CH),需要脑脊液 (CSF) 的转移.
- 在较低级别质瘤切除后,对CH的风险因素的了解较少.
研究的目的:
- 为了确定2级和3级质瘤切除后的水脑的发生率和时间.
- 为了确定这些患者在切割后发展CH的独立风险因素.
主要方法:
- 在2006年至2019年间,对346名经过质瘤切除 (世卫组织2级和3级) 的患者进行了回顾性分析.
- 评估患者数据,包括人口统计,瘤特征,手术事件 (心室开口,心室炎,再出血) 和结果.
- 单变量和多变量统计分析以确定CH的风险因素.
主要成果:
- 6.9%的患者需要在切割后进行CSF转移手术.
- 在5.5%的患者中,发生了沟通性水脑 (CH),中位数发生在切除后44天.
- 世卫组织3级,再出血,腹腔炎和脑下瘤的位置是CH的重要独立风险因素.
结论:
- 手术后的CH需要CSF轮流是低级质瘤切除后的风险,特别是在3级瘤.
- 肝炎通常在手术后几周表现出来.
- 再出血和术后腹腔炎是CH发展的重要独立风险因素.
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