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真实和想象中的针背后的甲状腺皮层机制真实和想象中的针
Qiao Kong1, Valeria Sacca1, Kathryn Walker1
1Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02129, USA.
Biomedicines
|July 29, 2023
概括
针和视频指导针成像治疗 (VGAIT) 激活了不同的甲状腺皮质网络来缓解疼痛. VGAIT显示了通过使用整感和任务积极网络来实现远程疼痛管理的潜力.
科学领域:
- 神经科学是一个神经科学.
- 疼痛管理 疼痛管理
- 医疗成像医学成像
背景情况:
- 针和指导图像治疗对慢性疼痛有希望,但它们的机制尚未完全理解.
- 甲状腺皮层通路对于感官处理和疼痛调节至关重要.
- 研究静止状态功能连接 (rsFC) 提供了对大脑网络活动的见解.
研究的目的:
- 探索针和视频引导针成像治疗 (VGAIT) 在疼痛管理中的甲状腺皮质机制.
- 为了比较由真实针引发的大脑网络改变,VGAIT和各自的对照.
- 为了将大脑网络的变化与疼痛值变化相关联.
主要方法:
- 一个在27名健康个体内的随机交叉设计研究.
- 利用了thalamic分区 (VPL,MD,Mthal) 的静止状态功能连接 (rsFC) 分析.
- 在不同条件下,与丘脑和皮层区域 (DMN,整感觉,运动,感觉网络) 之间的rsFC比较.
主要成果:
- 实体针调节的rsFC在丘脑和默认模式网络 (DMN) 和体感皮层之间.
- VGAIT增加了丘陵体和感官网络,运动和感官皮层之间的rsFC.
- 与真实针相比,VGAIT显示,与任务积极网络相比,thalamocortical rsFC更大,与疼痛值变化相关.
结论:
- 针和VGAIT止痛都涉及甲状腺皮层网络调节.
- 与单独针相比,VGAIT涉及不同的大脑网络,这表明了独特的治疗机制.
- 由于其独特的神经效应,VGAIT具有作为远程疼痛管理策略的潜力.
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