饮食与乳腺癌关系中的营养代谢学:当前的研究,挑战和未来的方向 - - 综述
Farhad Vahid1, Kimia Hajizadeghan2, Adeleh Khodabakhshi2
1Nutrition and Health Research Group, Precision Health Department, Luxembourg Institute of Health, 1445 Strassen, Luxembourg.
Biomedicines
|July 29, 2023
概括
营养代谢学通过分析代谢物来研究饮食如何影响乳腺癌风险. 这一领域提供了对预防和治疗乳腺癌的个性化饮食策略的见解.
科学领域:
- 代谢学 代谢学 代谢学
- 营养科学 营养科学
- 在瘤学瘤学.
背景情况:
- 全球乳腺癌发病率正在上升,饮食是关键可修改的危险因素.
- 饮食,新陈代谢和乳腺癌之间的复杂关系仍然不完全理解.
- 营养代谢学成为阐明这些饮食对癌症发展的影响的关键工具.
研究的目的:
- 综合审查目前关于营养代谢学应用的研究,以了解饮食与乳腺癌的联系.
- 为了确定与乳腺癌风险相关的特定代谢物和代谢途径.
- 讨论该领域的挑战和未来方向.
主要方法:
- 在主要的科学数据库 (PubMed,Scopus,Web of Science,Google Scholar) 进行系统的文献搜索.
- 包括体内和体外研究,检查饮食,代谢物和乳腺癌.
- 对乳腺癌研究中的营养代谢学现有知识的综合.
主要成果:
- 确定了特定的代谢物 (例如,皮佩林,卡普拉特) 和与乳腺癌风险相关的途径.
- 突出了营养代谢学的潜力,揭示了饮食与癌症的关系.
- 在标准化,数据解释和多学科集成方面存在公认的挑战.
结论:
- 营养代谢学表明,对促进乳腺癌研究有很大的前途.
- 这一领域可以为预防和治疗乳腺癌提供个性化的饮食建议.
- 未来的研究应该专注于肠道微生物群和整合多omics方法.
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