相关实验视频
Updated: Jul 21, 2025

Generation of a Mouse Spontaneous Autoimmune Thyroiditis Model
Published on: March 17, 2023
在斯普特尼克疫苗接种后,新出现的自身免疫疾病
Olga Vera-Lastra1, Gabriela Mora2, Abihai Lucas-Hernández3
1Internal Medicine Department, Hospital de Especialidades, Dr. Antonio Fraga Mouret, Centro Médico Nacional La Raza, Instituto Mexicano del Seguro Social (IMSS), Mexico City 02990, Mexico.
斯普特尼克COVID-19疫苗虽然通常是安全的,但已与新的自身免疫性疾病有关. 在接种疫苗的患者中,神经和血液疾病,包括血栓形成,最常见.
科学领域:
- 免疫学 免疫学 免疫学
- 疫苗学 疫苗学 疫苗学
- 神经学 神经学
背景情况:
- 迅速识别SARS-CoV-2刺激了疫苗的开发,包括像Sputnik这样的腺病毒载体疫苗.
- 接种疫苗后的自身免疫性疾病监测对于了解疫苗安全概况至关重要.
研究的目的:
- 为了调查在Sputnik COVID-19疫苗接种后自身免疫性疾病的表现.
- 为了确定斯普特尼克疫苗接种后自身免疫疾病的类型和频率.
主要方法:
- 一项回顾性研究分析了在接种斯普特尼克疫苗后出现新发自免疫疾病的患者.
- 从2021年3月到2022年12月,在墨西哥城和阿根廷的两家医院收集了数据.
主要成果:
- 28名患者 (平均年龄为56.9岁) 在斯普特尼克疫苗接种后发生了自身免疫性疾病.
- 神经 (46%) 和血液 (42%) 自身免疫性疾病是最常见的,包括血栓事件 (28%) 和自身免疫性血液溶解性贫血 (7.1%).
- 还观察到风湿学 (7.1%) 和内分泌系统 (3.5%) 的疾病.
结论:
- 斯普特尼克COVID-19疫苗虽然通常是安全的,但可以导致不良自身免疫事件.
- 血栓形成症和吉兰-巴雷综合征是这个队列中接种疫苗后最常见的自身免疫表现.
更多相关视频
05:55Author Spotlight: Novel Assay for Studying B-Cell Responses in Multiple Sclerosis Research
Published on: December 1, 2023
05:44A Rapid, Simple, and Standardized Homogenization Method to Prepare Antigen/Adjuvant Emulsions for Inducing Experimental Autoimmune Encephalomyelitis
Published on: December 9, 2022
相关概念视频
Autoimmune Disorders
Concept and Mechanism of Autoimmune Diseases
The immune...
Vaccinations
Immunological Memory
What is Immunological Memory?
Immunological memory is an integral function of the immune system that allows it to recognize and react more rapidly and effectively to pathogens previously encountered. This feature...
Immunodeficiency Diseases
There are three main causes of immunodeficiency...
Antigens Involved in Adaptive Immunity
Complete Antigens
Complete antigens possess both immunogenicity and...
Skin Diseases and Disorders
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...