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Updated: Jul 21, 2025

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侧链修改的索氨酸衍生物具有抗菌素活性

Dongguang Fan1, Bin Wang2, Giovanni Stelitano3

  • 1College of Pharmaceutical Sciences, Soochow University, Suzhou 215123, China.

Biomedicines
|July 29, 2023
PubMed
概括

通过抑制Mycobacterium tuberculosis (Mtb) DprE1.1,新的西 (BTZ) 类似物可以对抗结核病 (TB). 化合物37显示出更好的溶解性和生物可用性,在这种传染性疾病的小鼠模型中显示出有效性.

关键词:
这是一种DprE1抑制剂.抗结核剂是一种抗结核剂.在体内活动活体活动.结构 结构 活动 关系 关系

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