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Updated: Jul 21, 2025

Simultaneous Quantification of Selected Kynurenines Analyzed by Liquid Chromatography-Mass Spectrometry in Medium Collected from Cancer Cell Cultures
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印度列胺2,3-二氧化酶 (IDO) 活性:在瘤免疫疗法中实验室确定前景生物标志物

Pengbo Yang1, Junhua Zhang2

  • 1Department of Laboratory Medicine, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing 100730, China.

Biomedicines
|July 29, 2023
PubMed
概括

印度列胺2,3-二氧化酶1 (IDO1) 对于免疫耐受性和癌症免疫疗法至关重要. IDO活性测试对于评估人体血液中的IDO1抑制剂用于瘤治疗有价值.

关键词:
IDO 抑制剂的使用.生物标志物生物标志物酶活性的酶活性.免疫反应的免疫反应.氨酸 2,3-二氧化基酶的存在基诺氨酸通路的使用

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Tumor Immunotherapy01:27

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Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
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