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Updated: Jul 21, 2025

Uptake of New Lipid-coated Nanoparticles Containing Falcarindiol by Human Mesenchymal Stem Cells
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叶酸功能化纳米粒子药物输送系统的评估-有效性和担忧

Muhammad Aiman Irfan Ibrahim1, Rozana Othman1,2, Chin Fei Chee3

  • 1Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Universiti Malaya, Kuala Lumpur 50603, Malaysia.

Biomedicines
|July 29, 2023
PubMed
概括

叶酸功能化纳米颗粒对癌症药物输送有希望,但体内研究显示,肝脏吸收等挑战限制了瘤向有效性. 需要进一步的研究来优化这些系统用于临床使用.

关键词:
叶酸受体向性的受体叶酸受体 叶酸受体 叶酸受体叶酸是一种叶酸.低瘤选择性的瘤选择性.纳米粒子药物递送系统

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Factors Affecting Dissolution: Particle Size and Effective Surface Area01:23

Factors Affecting Dissolution: Particle Size and Effective Surface Area

Dissolution kinetics, an essential aspect of oral drug delivery, is significantly influenced by the drug's particle size. According to the Noyes-Whitney dissolution model, the dissolution rate correlates directly with the drug's surface area. The larger the surface area, the higher the drug's solubility in water, leading to a faster drug dissolution rate. Reducing particle size increases the effective surface area, enhancing the dissolution process. Micronization and nanosizing are...
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