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烯酸盐用于治疗慢性静脉缺陷:一个回顾性观察单中心研究

Nicolas Falvo¹, Amine Latreche¹, Olivier Chevallier¹

¹Image-Guided Therapy Center, ICMUB Laboratory, UMR CNRS 6302, Department of Vascular and Interventional Radiology, François-Mitterrand University Hospital, 14 Rue Paul Gaffarel, BP 77908, 21079 Dijon, France.

Diagnostics (Basel, Switzerland)

|July 29, 2023

概括

静脉内烯酸切除为慢性表面静脉疾病提供了安全有效的替代方案,达到94%的闭合率. 这种方法可以避免腹麻醉和与热性消融相关的热性神经损伤.

科学领域:

血管外科血管外科
最少侵入性手术的方法
医疗器械技术医疗器械技术

背景情况:

内静脉热疗法是慢性表面静脉疾病的常见方法,但有诸如瘤麻醉和神经损伤风险等缺点.
静脉内烯酸盐切除提供了一个新的替代方案,没有这些特定的限制.

研究的目的:

为了评估内静脉烯酸盐切除治疗慢性表面静脉疾病的有效性和安全性.
为了确定与18个月的目标静脉关闭相关的因素.
评估对患者生活质量的影响,并记录不良事件.

主要方法:

从2018年到2021年,对55名成年患者 (67个经过治疗的静脉) 进行了回顾性观察研究.
18个月的随访评估目标静脉关闭,生活质量 (SF-36, VEINES-QOL/Sym) 和不良事件.
分析预测静脉再通道化的因素,特别是目标静脉直径.

主要成果:

在18个月后,观察到高目标静脉关闭率为94% (95% CI,85-98%).
目标静脉直径≥9.5毫米是再通道化的预测指标 (81%的灵敏度,75%的特异性).
报告说,生活质量得分有显著改善 (p < 0.001).

结论:

在经验丰富的手中,静脉内烯酸除对于治疗慢性表面静脉疾病是非常有效和安全的.
需要进一步的研究来优化对较大的静脉 (≥9.5毫米) 的协议,以潜在地增加关闭率.

关键词:

通过静脉内注射的蓝烯酸除.人们的生活质量.静脉功能不充分静脉功能不足

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