四象限宫活检的价值在女性与不同的大肠镜印象不同
Mandy Man-Yee Chu1, Charleen Sze-Yan Cheung1, Siew-Fei Ngu1
1Department of Obstetrics and Gynecology, The University of Hong Kong, Queen Mary Hospital, Hong Kong.
Diagnostics (Basel, Switzerland)
|July 29, 2023
概括
四象限活检在检测高度的宫内皮质瘤 (CIN) 方面比镜导向活检更有效. 这种方法特别推给有异常宫查结果或阳性HPV测试的女性.
科学领域:
- 妇科 妇科 妇科 妇科
- 在瘤学瘤学.
- 病理学 病理学 病理学
背景情况:
- 宫癌查依赖于检测宫内皮质瘤 (CIN).
- 准确诊断高度CIN对于有效治疗和预防侵袭性宫癌至关重要.
- 目前的诊断方法包括镜导向活检,但其在检测所有CIN病例中的有效性仍有争议.
研究的目的:
- 为了比较结肠镜导向活检与四象限活检的诊断准确性,用于识别高度CIN.
- 为了评估这些活检技术在不同类别的结肠镜印记的有效性.
主要方法:
- 一项前性研究,涉及1311名接受细胞学异常或阳性HPV检测的宫查的妇女.
- 进行了结肠镜检查,随后进行了结肠镜导向活检和四象限活检 (三点,六点,九点和十二点),并进行了内宫切.
- 通过比较每个活检方法的高度CIN检测率来评估诊断疗效.
主要成果:
- 四象限活检检测出明显更多的高度CIN (86.4%),相比于镜导向活检 (50.8%) (p < 0.0001).
- 高度CIN在正常或不令人满意的结肠镜检查的情况下被诊断为22.9%的病例.
- 在低度结肠镜印记的病例中,四象限活检发现了明显更多的高度CIN (82.8%),而不是结肠镜导向活检 (56.3%) (p = 0.0011).
结论:
- 四象限宫活检显示,高度CIN的诊断效果优于镜导向活检.
- 对于所有患有异常宫涂抹或阳性HPV测试的妇女,特别是那些低度,正常或不令人满意的结肠镜检查结果的妇女,应考虑使用这种技术.
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