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通过感染检测糖尿病酸性酸症:用实用诊断工具对抗危及生命的紧急情况

Rahnuma Ahmad¹, Mahendra Narwaria², Arya Singh²

¹Department of Physiology, Medical College for Women and Hospital, Dhaka 1230, Bangladesh.

Diagnostics (Basel, Switzerland)

|July 29, 2023

概括

糖尿病酸症 (DKA) 是一种严重的糖尿病并发症,通常是由感染引发的. 在DKA患者中,早期诊断感染对于及时治疗和预防抗生素耐药性至关重要.

科学领域:

内分泌学和糖尿病管理
传染性疾病传染性疾病
临床诊断临床诊断临床诊断

背景情况:

糖尿病酸性酸症 (DKA) 是一种危及生命的糖尿病并发症,死亡率为2-5%.
感染是DKA的主要触发因素,约占病例的50%,通常是由于尿路感染或肺炎.
从单独的DKA中区分DKA与感染至关重要,以防止不必要的抗生素使用和打击抗菌素耐药性.

研究的目的:

审查用于诊断DKA患者感染的败血症标志物.
要区分感染的DKA与没有感染的DKA.
提高人们对DKA与感染的严重程度以及及时诊断的需要的认识.

主要方法:

对现有文献进行了叙事审查.
在Google Scholar上使用与DKA,感染和生物标志物相关的关键词进行了搜索.
检查了对DKA中的Procalsitonin,炎症性细胞因子,乳酸性酸性疾病和白细胞计数的相关研究.

主要成果:

DKA症状和感染生物标志物 (例如发烧,CRP,WBC) 可能会重叠,使诊断复杂化.
细菌培养是确认性的,但耗时 (长达24小时),延迟了关键治疗.
确定可靠的DKA感染生物标志物对于立即的急诊室管理至关重要.

结论:

早期和准确的DKA感染诊断对于有效的管理和改善患者结果至关重要.
在DKA中感染的生物标志物可以帮助及时做出治疗决定,特别是在等待细菌培养结果时.
对DKA感染的诊断工具的进一步研究是有必要的,以优化患者护理和打击抗生素耐药性.

关键词:

细菌感染细菌感染生物标志物生物标志物糖尿病酸性酸性糖尿病早期诊断早期诊断早期诊断紧急情况紧急情况这是一种炎症炎症炎症炎症.这是一种血症.

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