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Updated: Jul 21, 2025

Development of an in vitro model system for studying the interaction of Equus caballus IgE with its high-affinity receptor FcεRI
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Development of an in vitro model system for studying the interaction of Equus caballus IgE with its high-affinity receptor FcεRI

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表达马匹MHC的高分辨率基因定型揭示了高度复杂的MHC结构结构

Deepali Vasoya1, Thomas Tzelos1,2, Lindert Benedictus3

  • 1The Roslin Institute, The Royal (Dick) School of Veterinary Studies, University of Edinburgh, Easter Bush Campus, Roslin EH25 9RG, UK.

Genes
|July 29, 2023
PubMed
概括

高通量测序揭示了马群中广泛的主要基因相容性复合体 (MHC) 多样性. 这项研究描述了新的马匹MHCI和MHCII序列,突出了特定品种的变异和更广泛的种群多样性.

关键词:
主要组织相容性复合体 (MHC)品种多样性 品种多样性马类的马类动物.高通量测序的高通量测序多形态主义的多态主义.

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相关概念视频

Epistasis01:39

Epistasis

In addition to multiple alleles at the same locus influencing traits, numerous genes or alleles at different locations may interact and influence phenotypes in a phenomenon called epistasis. For example, rabbit fur can be black or brown depending on whether the animal is homozygous dominant or heterozygous at a TYRP1 locus. However, if the rabbit is also homozygous recessive at a locus on the tyrosinase gene (TYR), it will have an unshaded coat that appears white, regardless of its TYRP1...
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