评价糖尿病足严重性的分类系统:对影响生存的因素进行了12年的回顾性研究
Otilia Niță1, Lidia Iuliana Arhire1, Laura Mihalache1
1Faculty of Medicine, University of Medicine and Pharmacy "Grigore T Popa", 700115 Iasi, Romania.
Healthcare (Basel, Switzerland)
|July 29, 2023
概括
糖尿病足 (DFU) 显著增加死亡风险,特别是涉及骨或关节的严重病例. 诸如脏病和心血管疾病等因素也导致DFU患者的生存结果不佳.
科学领域:
- 内分泌学 在内分泌学.
- 腎臟病學 (nephrology) 是一種醫學專業.
- 心脏病学 心脏病学
- 足部医学是一门专业.
背景情况:
- 糖尿病足 (DFU) 是糖尿病的一个严重并发症.
- 在DFU诊断后患者的存活率是一个关键的公共卫生问题.
- 了解影响DFU患者结果的因素对于改善临床管理至关重要.
研究的目的:
- 调查糖尿病足 (DFU) 患者的生存率.
- 确定与DFU患者死亡率增加相关的关键因素.
- 分析DFU严重程度对患者存活时间的影响.
主要方法:
- 在2007年至2017年期间,对659名DFU患者进行了回顾性研究.
- 随访患者至2020年12月 (13年期间).
- 对影响死亡率的人口,临床和DFU相关因素的分析.
主要成果:
- 总共有278例死亡 (42.2%) 记录,平均存活时间为9年.
- 显著的死亡率贡献者包括住院时间长,糖尿病脏病,慢性脏病,淋巴细胞过率,心血管疾病,高血压和贫血.
- 严重的DFU (涉及肌,关节或骨) 在调整为混因素后与显著更高的死亡风险相关 (HR 1.889-2.333).
结论:
- 患有严重的DFU的患者面临着大幅增加的死亡风险.
- 严重程度的DFU,特别是深层组织的参与,是低生存率的独立预测指标.
- 综合管理应对并发症和的严重程度对于改善DFU患者预后至关重要.
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