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Updated: Jul 21, 2025

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A Novel Method: Super-selective Adrenal Venous Sampling
Published on: September 15, 2017
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上腺:对文献的系统审查
Nikola Gligorijevic1, Marija Kaljevic2,3, Natasa Radovanovic4
1Division of General Internal Medicine, Department of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA.
Journal of clinical medicine
|July 29, 2023
概括
上腺通常是真菌感染,通常是由Histoplasma capsulatum引起的,导致双边参与和潜在的长期上腺功能不充分. 血小板缺血是这些罕见病例中死亡率的关键预测因素.
科学领域:
- 内分泌学 在内分泌学.
- 传染性疾病 传染性疾病
- 放射学 放射学是指放射学
背景情况:
- 上腺是罕见但严重的感染.
- 了解它们的病因学,表现和结果对于患者管理至关重要.
研究的目的:
- 系统地审查和总结关于上腺的当前知识.
- 详细介绍上腺的病因学,临床和实验室发现,成像特征,管理策略和预后.
主要方法:
- 2017年至2022年间发表的文章的系统文献综述.
- 使用与上腺和感染相关的术语搜索了PubMed.
- 包括来自73篇文章的数据,分析了84例患者病例.
主要成果:
- 大多数患者是男性 (81%),平均年龄为55岁. 常见的症状包括体重减轻 (58.3%) 和发烧 (49%).
- 常见的发现是皮质醇低 (51.9%),ACTH升高 (43.2%),低血 (88.2%) 和贫血 (83.3%). 囊性质是主要的原因 (37.3%).
- 往往是双边的 (70%),其中46.4%患上上腺功能不全. 存活率为92.9%,血小板缺血作为死亡的独立风险因素.
结论:
- 上腺通常是真菌的,特别是Histoplasma capsulatum,通常是双边的,由传播感染引起.
- 长期上腺功能缺陷是一个显著的并发症 (46.4%).
- 死亡率约为7%,血小板缺血表明预后较差,需要进一步研究最佳管理.
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