呼吸障碍在后急性COVID-19:一个多参数心肺评估
Antonella Cecchetto1, Gabriella Guarnieri2, Gianpaolo Torreggiani1
1Department of Cardiac Thoracic Vascular Sciences and Public Health, University of Padua, 35128 Padua, Italy.
Journal of clinical medicine
|July 29, 2023
概括
在COVID-19住院后,持久性呼吸不良是常见的. 预测因素包括C反应性蛋白,住院时间和体重指数,而脱和右心室功能障碍与持续的呼吸困难有关.
科学领域:
- 肺部病理学 肺部病理学
- 心脏病学 心脏病学
- 传染性疾病 传染性疾病
背景情况:
- 后急性COVID-19经常涉及持续性呼吸困难,不清楚潜在的病理生理学.
- 了解预测和与呼吸障碍相关的因素对于患者管理至关重要.
研究的目的:
- 在COVID-19住院后的随访期间评估呼吸障碍的患病率.
- 在入院和随访时确定与持久性呼吸障碍相关的因素.
主要方法:
- 一组225名因中度至重度COVID-19肺炎住院的患者接受了临床评估,实验室测试,心声扫描,六分钟步行测试 (6MWT) 和出院五个月后的肺功能测试.
- 统计分析确定了呼吸障碍的独立预测因素和相关因素.
主要成果:
- 51名患者报告持续性呼吸障碍.
- 入院时呼吸障碍的预测因素包括C反应蛋白,更长的住院时间和更高的体重指数.
- 在随访时,在6MWT期间绝对的SpO2下降,右心室全球纵向应变,和RV全球纵向应变/静脉性肺动脉压力比率与呼吸不全有关.
结论:
- 呼吸障碍是COVID-19肺炎住院患者常见的后果.
- 虽然CRP,BMI和住院时间等入院因素预测持续性呼吸障碍,但随访结果如脱和RV功能障碍与其存在有关.
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