胆道关节的功能障碍是临床,诊断和治疗方面的挑战
Marina Kegnæs1, Srdan Novovic1,2, Daniel Mønsted Shabanzadeh3
1Pancreatitis Centre East, Gastrounit, Copenhagen University Hospital-Amager and Hvidovre, Hvidovre, 1172 Copenhagen, Denmark.
Journal of clinical medicine
|July 29, 2023
概括
胆囊切除后,奥迪功能障碍 (SOD) 的道会引起疼痛. 虽然手术有助于一些患者,但它存在风险,需要更好的治疗方法,特别是药理疗法.
科学领域:
- 胃肠病学 胃肠病学
- 肝胆道手术 肝胆道手术
背景情况:
- 奥迪功能障碍的胆管 (SOD) 是胆囊切除术后持续疼痛的重要原因.
- 目前对SOD的诊断和治疗策略有限,需要在现场进行更新.
研究的目的:
- 审查和更新有关胆汁SOD的诊断和治疗的当前知识.
- 发现研究中的差距,并强调进一步临床试验的必要性.
主要方法:
- 文献综述侧重于胆汁SOD的诊断标准和治疗干预措施.
- 对各种治疗方式的疗效和安全现有数据的分析.
主要成果:
- 有限的证据支持1型和2型SOD的胆脉缩切除术,但不是3型.
- 线切除术与10-15%的治疗后胰腺炎发生率有关.
- 对SOD的药理疗法仍然缺乏探索,缺乏可靠的临床试验数据.
结论:
- 改善诊断,患者选择和治疗方式对于管理SOD至关重要.
- 对于药物和非药物SOD治疗的高质量,随机化,假冒/安慰剂对照试验存在重大未满足的需求.
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