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Updated: Jul 21, 2025

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过渡网络揭示了由糖氨基甘油或脂质引起的Aβ中的混乱到秩序转换

Moritz Schäffler1,2, Suman Samantray1, Birgit Strodel1,2

  • 1Institute of Biological Information Processing, Structural Biochemistry (IBI-7), Forschungszentrum Jülich, 52428 Jülich, Germany.

International journal of molecular sciences
|July 29, 2023
PubMed
概括

阿尔茨海默病的研究揭示了粉样β (Aβ) 如何在糖氨基 (GAG) 和脂质附近改变形状. 这些由不同的机制驱动的形状变化影响了Aβ聚合和阿尔茨海默病的发病.

关键词:
粉样化物-β-β 的存在.从混乱到秩序的转变.本质上是无序的蛋白质.分子动力学模拟,分子动力学模拟过渡网络的过渡网络

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