主要类型的瘤治疗中的免疫反应
Patrycja Kozubek1, Julia Wołoszczak1, Krzysztof Gomułka2
1Student Scientific Group of Adult Allergology, 50-369 Wrocław, Poland.
International journal of molecular sciences
|July 29, 2023
概括
化疗等癌症治疗可以引起严重的过敏和皮肤反应,有时导致死亡. 本综述综合了自2016年以来的研究,以更好地了解和预防这些不良事件.
科学领域:
- 在瘤学瘤学.
- 皮肤病学 皮肤病学
- 药理学 药理学是指药理学的学科.
背景情况:
- 化疗和生物治疗是有效的癌症疗法.
- 这些治疗可以引起严重的过敏和皮肤学副作用.
- 副作用的范围从轻微的皮疹到危及生命的疾病,如史蒂文斯-约翰逊综合征.
研究的目的:
- 审查和系统化有关瘤治疗不良反应的当前知识.
- 突出需要进一步研究预防这些副作用的必要性.
- 为临床实践提供有关癌症治疗期间患者安全的信息.
主要方法:
- 自2016年以来出版的研究文件的系统审查.
- 对过敏和皮肤反应的文献分析.
- 综合关于严重皮肤不良反应 (SCAR) 的信息.
主要成果:
- 各种过敏反应 (I-IV型) 和皮肤反应是常见的.
- 严重的反应包括史蒂文斯-约翰逊综合征,有毒表皮解等.
- 由于不良事件的治疗中断可能会对患者的生存产生负面影响.
结论:
- 对癌症治疗的不良反应构成了重大的临床挑战.
- 进一步的研究对于制定减轻这些副作用的策略至关重要.
- 积极主动管理和对不良事件的理解对于改善患者的治疗结果至关重要.
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