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Updated: Jul 21, 2025

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用CRISPR/Cas9 RNPs预装的不同复原病毒样粒子的深度表征和比较

Max Wichmann1, Cecile L Maire2, Niklas Nuppenau1

  • 1Research Department Cell and Gene Therapy, Department of Stem Cell Transplantation, University Medical Centre Hamburg-Eppendorf (UKE), 20246 Hamburg, Germany.

International journal of molecular sciences
|July 29, 2023
PubMed
概括

增强的复原病毒样粒子 (egRVLP) 在CRISPR/Cas基因编辑交付方面表现出卓越的效率. 这些先进的VLP提供了高淘汰率,最小的目标外影响,为更安全的临床应用铺平了道路.

关键词:
这就是CRISPR/CasPR.iPS 细胞 细胞 iPS 细胞类似病毒的颗粒.

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