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了解SARS-CoV-2的ORF6行动机制的洞察力

Elena Krachmarova1, Peicho Petkov2, Elena Lilkova3

  • 1Institute of Molecular Biology "Acad. Roumen Tsanev", Bulgarian Academy of Sciences, 1113 Sofia, Bulgaria.

International journal of molecular sciences
|July 29, 2023
PubMed
概括

SARS-CoV-2的ORF6蛋白抑制免疫反应,并通过将RAE1困在细胞质中,破坏mRNA运输和DNA复制,导致细胞毒性. 这影响病毒病原性,并提供治疗点.

关键词:
3D分子结构建模 3D分子结构建模DNA复制的压力是DNA复制的压力.在R-Loop中使用.在SARS-CoV-2的ORF6RAE1结合过程中.细胞循环中的细胞循环.环林E 环林E 环林分子动力学模拟的模拟.

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