在创伤性脊髓损伤中介质干细胞疗法:系统性审查
Rodrigo Montoto-Meijide1, Rosa Meijide-Faílde2,3, Silvia María Díaz-Prado2,3
1Complejo Hospitalario Universitario de Santiago de Compostela, 15706 Santiago de Compostela, Spain.
International journal of molecular sciences
|July 29, 2023
概括
介质干细胞 (MSC) 治疗对创伤性脊髓损伤 (TSCI) 恢复有希望,改善神经功能并证明短期安全性. 需要进一步研究长期疗效和更广泛的应用.
科学领域:
- 神经科学是一个神经科学.
- 再生医学是一种再生医学.
- 临床试验 临床试验
背景情况:
- 创伤性脊髓损伤 (TSCI) 由于中枢神经系统再生能力有限,因此存在重大挑战.
- 细胞疗法,特别是使用介质干细胞 (MSC),是TSCI治疗的有希望的途径.
结论:
- MSC治疗显示了TSCI的治疗潜力,提供了短期到中期的益处和安全性.
- 有限的证据要求在推一般化方面谨慎行事;长期的安全性和有效性需要进一步调查.
- 未来的研究应该探索基因疗法,神经刺激和组织工程,以实现全面的TSCI治疗策略.
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