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发育回归之后的和攻击性:自闭症谱系障碍中的新综合征?
John Gaitanis1, Duyu Nie1, Tao Hou2
1Hasbro Children's Hospital, The Warren Alpert Medical School of Brown University, Providence, RI 02903, USA.
Journal of personalized medicine
|July 29, 2023
概括
自闭症谱系障碍与回归 (ASD-R) 与更高的率和攻击性行为有关. 这些并发症可能会导致ASD-R儿童的二次回归,影响他们的生活质量.
科学领域:
- 神经发育障碍 神经发育障碍
- 儿科神经学 儿科神经学
- 儿童心理学 儿童心理学
背景情况:
- 自闭症谱系障碍与回归 (ASD-R) 涉及发展里程碑的损失.
- 诸如攻击性和等并发症在患有自闭症的老年儿童中很常见.
- 这些条件可能会阻碍社会和语言的发展.
研究的目的:
- 调查ASD-R患者与没有回归 (ASD-NR) 患者相比,和攻击性行为是否更普遍.
- 分析和攻击性在ASD-R患者的综合影响.
主要方法:
- 对12岁以上非综合征性ASD患者的回顾性审查.
- 在ASD-R和ASD-NR组之间比较和侵略率.
- 统计分析共发病率的流行情况.
主要成果:
- 患有ASD-R患者的发病率 (51.8%对38.1%) 和侵略性 (73.2%对57.1%) 不显著增加.
- 在ASD-R与ASD-NR (44.5%与23.8%) 中,和侵略的联合率在统计学上显著.
- 具有侵略性的似乎在ASD-R患者中更常见.
结论:
- 在患有ASD-R的人群中,和攻击性行为更频繁地一起观察到.
- 这些并发症可能导致"第二次回归",显著影响生活质量.
- 建议进行进一步的前性研究,以确认发现并确定开发时间表.
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