慢性阻塞性肺部疾病的并发症过程的分析
1Department of Nursing, Ryazan State Medical University, 390026 Ryazan, Russia.
Journal of personalized medicine
|July 29, 2023
概括
动脉样性心血管疾病 (ASCVD) 是最常见的并发症,也是慢性阻塞性肺病 (COPD) 患者死亡的主要原因. 管理ASCVD对于改善COPD患者的生存率至关重要.
科学领域:
- 肺部医学 肺部医学
- 心血管医学 心血管医学
- 临床研究 临床研究
背景情况:
- 慢性阻塞性肺病 (COPD) 呈现异质的临床过程,并且经常与并发症相关.
- 动脉样性心血管疾病 (ASCVD) 显著影响COPD的自然史和患者的预后.
- 了解COPD和ASCVD之间的相互作用对于有效的患者管理至关重要.
研究的目的:
- 研究动脉样性心血管疾病 (ASCVD) 对慢性阻塞性肺病 (COPD) 的过程和结果的长期 (15年) 影响.
- 确定伴随性ASCVD的男性COPD患者死亡率的预后因素.
主要方法:
- 一项纵向研究涉及170名被诊断患有COPD的男性患者.
- 数据收集包括螺旋计,症状严重程度,危险因素和并发症.
- 用Kaplan-Meier方法分析了预后因素和生存率.
主要成果:
- 在COPD患者中,ASCVD是最常见的并发症和首要死亡原因.
- 与没有ASCVD的患者相比,患有COPD的ASCVD患者经历了更严重的呼吸障碍,频繁的恶化和减少的生存期 (p < 0.01).
- 在COPD患者中增加ASCVD死亡风险的因素包括年龄>60,快速FEV1下降,每年>2次恶化和>30包年吸烟史. 高查尔森并发症指数得分表明疾病过程更严重,预后更差.
结论:
- 动脉样性心血管疾病 (ASCVD) 显著影响疾病进展,是慢性阻塞性肺病 (COPD) 患者死亡率的主要决定因素.
- 对伴随性疾病的评估,特别是对于ASCVD,以及风险因子分层对于管理COPD患者和改善其生存结果至关重要.
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