与SARS-CoV-2菌株相关的长期COVID症状的发生率
Teresita Aloè1, Federica Novelli2, Gianfranco Puppo2
1Interventional Pulmonology Unit, IRCCS Ospedale Policlinico San Martino, Largo Rosanna Benzi 10, 16100 Genoa, Italy.
Life (Basel, Switzerland)
|July 29, 2023
概括
长期COVID症状在SARS-CoV-2菌株之间没有显著差异,除了与经典变种相关的疼痛. 这强调了需要多学科的后COVID护理,包括心理健康支持和康复.
科学领域:
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
- 临床医学 临床医学
背景情况:
- 关于与特定SARS-CoV-2菌株相关的长期COVID (L-COVID) 症状模式的研究有限.
- 了解这些差异对于有针对性的患者管理和公共卫生战略至关重要.
研究的目的:
- 探索急性感染特征与持续的L-COVID症状之间的联系.
- 分析不同SARS-CoV-2菌株中L-COVID的临床表现.
主要方法:
- 一项观察性多中心研究,涉及308名意大利患者 (2020年3月至2022年3月).
- 人口统计,临床数据,感染严重程度和L-COVID症状 (疲劳,呼吸不良,生活质量) 在基线和6个月后续记录.
主要成果:
- 肥胖患病率在感染波之间有显著差异 (p=0.012).
- 治疗策略不断发展,在第一波增加了侵入性通风,在第四波增加了氧气治疗.
- 在随访时,呼吸不良,疲劳和一些生活质量领域 (移动性,通常活动,疼痛) 得到改善,但在通常的护理或焦虑抑郁症方面没有改善.
结论:
- 跨菌株之间没有发现常见L-COVID症状的显著差异,除了与古典变种更高的疼痛域相关.
- L-COVID对社会,职业和日常活动产生了重大影响.
- 多学科的后续护理,包括心理健康和康复,对于L-COVID患者至关重要.
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