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通过皮肤进行脊髓刺激可促进COVID-19后急性患者的呼吸功能表现

Alexander Ovechkin^1,2,3, Tatiana Moshonkina⁴, Natalia Shandybina⁴

¹Kentucky Spinal Cord Injury Research Center, University of Louisville, Louisville, KY 40202, USA.

Life (Basel, Switzerland)

|July 29, 2023

概括

脊髓穿皮刺激 (scTS) 通过增强呼吸和呼吸肌肉活动,改善了COVID-19后患者的呼吸功能. 这种神经调节对COVID-19呼吸系统康复策略有希望.

科学领域:

神经学神经学
呼吸系统医学呼吸系统医学
康复康复康复康复

背景情况:

COVID-19 可能导致呼吸道和中枢神经系统功能障碍.
制定有效的康复策略,以应对COVID-19后的呼吸系统缺陷至关重要.

研究的目的:

评估脊髓穿皮刺激 (scTS) 对呼吸功能的神经调节作用.
在健康对照组和COVID-19后呼吸缺陷患者中评估scTS.
探索scTS作为一个潜在的康复策略.

主要方法:

一项前后,干预性,病例控制的研究,涉及10名COVID-19后患者和8名健康对照.
一次20分钟的模块化单相scTS应用到T5和T10脊髓段.
在scTS之前和之后评估呼吸系统参数,包括FVC,PIF,PEF,tPIF和tPEF.

主要成果:

在COVID-19后的患者中,scTS显著增加了PIF和PEF,同时降低了TPIF和TPEF.
健康对照显示PIF增加和TPIF降低,但PEF降低和TPEF增加.
在干预后,强迫生命能力 (FVC) 在两组中保持不变.

结论:

在COVID-19后的患者中,scTS促进了呼吸和呼气脊髓神经网络的激发.
在这些患者中,scTS会立即改善呼吸功能表现.
这种神经调节方法是COVID-19呼吸系统康复计划的可行选择.

关键词:

在 COVID-19 疫情中,通过神经调节进行神经调节.康复康复康复康复康复康复呼吸系统呼吸系统呼吸系统脊髓刺激脊髓刺激

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