额头年化和血栓栓塞的风险
Paula Cristina Morariu1,2, Daniela Maria Tanase1,2, Diana Elena Iov1,2
1Department of Internal Medicine, University of Medicine and Pharmacy "Grigore T. Popa", 16 University Street, 700115 Iasi, Romania.
Life (Basel, Switzerland)
|July 29, 2023
概括
中心环状化 (MAC) 与心房动 (AF) 患者的高血栓栓塞 (TE) 风险有关. 将MAC添加到风险分数中可能会改善血管疾病的预测.
科学领域:
- 心脏病学 心脏病学
- 血管医学 血管医学
背景情况:
- 目前对心房 (AF) 的血栓栓塞 (TE) 风险评分不包括心肌环状化 (MAC).
- MAC可能作为潜在血管疾病的指标,可能会影响TE风险评估.
研究的目的:
- 调查MAC和已确定的TE风险得分之间的相关性 (CHADS和CHA,DS和VASc).
- 为了比较患有MAC和没有MAC的患者的临床和心声学数据.
- 确定MAC是否是血管疾病的独立风险因素.
主要方法:
- 一项前性研究,包括103名有或没有AF的患者.
- 通过心声回声学评估MAC的存在.
- 计算CHADS 2和CHA 2 DS 2 -VASc分数的方法. 这是一个非常简单的方法.
- 分析临床数据,包括高血压,糖尿病,心力衰竭和中风史.
主要成果:
- 在50.5%的患者中,MAC被发现.
- 患有MAC的患者的CHADS2 (2.88对2.24,p=0.005) 和CHA2DS2-VASc (5.21对3.92,p<0.001) 分数显著更高.
- 左心室喷射分数与MAC存在负相关 (r=-0.254,p=0.01).
- 马克是血管疾病的重要危险因素 (OR=2.47,p<0.001).
结论:
- 中心环状化与AF患者的血栓栓塞风险得分增加有关.
- 存在MAC可以独立预测血管疾病的风险更高.
- 将MAC纳入TE风险分层可以提高血管事件的预测准确性.
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